Laboratoire de Chimie Moléculaire et Thio-organique

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Pr Didier VILLEMIN

Emeritus Professor

Section du Comité National n° 16
Section du CNU n° 32

Assistant in Biochemistry at P.et M. Curie University (UPMC) (1975-1979) in Paris.
Associate Professor in organic chemistry at the National School of Chemistry of Paris (ENSCP, now Paris Tech Chemistry) (1979-1985).
Full Professor at the ISMRa-National School of Engineers of Caen (ENSICAEN) (1985-2015).
Professor Emeritus at ENSICAEN since 2015.

Research interests

Green chemistry: pioneer in: solventless reactions (1984), flow reactions (1985) reactions under microwave activation (1989).
Catalysis: pioneer in olefins (1974) and alkynes (1982) metathesis.
Cheminformatics (QSAR, QSPR): pioneer in experts systems (1985), neural networks (1993), SVM (2010), graph kernels (2012) applications in organic chemistry.

Scientific records

More than 360 publications (chemistry and cheminformatics)
More than 30 conferences

Key publications

Experimental proof of the mechanism of Chauvin for ROMP: J.Organomet. Chem., 1978, 146, 259-265; doi: 10.1016/S0022-328X(00)88753-7.

First synthesis of natural products by RCM: Tetrahedron Lett., 1980, 21, 1715-1718; doi: 10.1016/S0040-4039(00)77818-X.

First reactions without solvent in microwaves: J. Chem. Soc. Chem. Commun., 1989, 386-387; doi: 10.1039/C39890000386.

Organometallic under microwaves, CH activation: J. Organometal. Chem., 1994, 479, 153-157.

Chiral ionic liquid in capillary electrophoresis: J. Chrom. A, 2007, 1155, 134-141; doi: 10.1002 / ejoc.200600556.

Organic synthesis under flow: Eur. J. Org. Chem., 2010, 333-337; doi: 10.1002 / ejoc.20091032.

Enzymes supported on magnetic nanoparticles: Sensors Actuators B, 2014, 192, 269-274; doi: 10.1016 / j.snb.2013.09.096; Phosphorous, Sulfur and Silicone 2015, 190, 879-890; doi: 10.1080 / 10426507. 2014.981633.

Cheminformatics:

Neural networks in QSPR: J. Chem. Soc. Faraday Trans., 1994, 90, 97-102; doi: 10.1039 / FT9949000097.

Graph kernels and stereochemistry: Pattern Recogn. Let., 2017, 87, 227-230; doi: 10.1016 / j.patrec.2016.06.025.

Book

Phosphonic and Aminophosphonic acids. Synthesis and applications.
Mohamed Amine Didi, Didier Villemin
Editions Universitaires Européennes, OmniScriptum Publising, Saarbrücken
2018, ISBN : 978-620-2-27586-6