Laboratoire de Chimie Moléculaire et Thio-organique

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Pr Didier VILLEMIN

Emeritus Professor

Section du Comité National n° 16
Section du CNU n° 32
Tel : +33231452840
e-mail : villemin@ensicaen.fr

  • Assistant in Biochemistry at P.et M. Curie University (UPMC) (1975-1979) in Paris.
  • Associate Professor in organic chemistry at the National School of Chemistry of Paris (ENSCP, now Paris Tech Chemistry) (1979-1985).
  • Full Professor at the ISMRa-National School of Engineers of Caen (ENSICAEN) (1985-2015).
  • Professor Emeritus at ENSICAEN since 2015.
     

Research interests

 

  • Green chemistry: pioneer in: solventless reactions (1984), flow reactions (1985) reactions under microwave activation (1989).
  • Catalysis: pioneer in olefins (1974) and alkynes (1982) metathesis.
  • Cheminformatics (QSAR, QSPR): pioneer in experts systems (1985), neural networks (1993), SVM (2010), graph kernels (2012) applications in organic chemistry.

 

Scientific records

 

  • More than 360 publications (chemistry and cheminformatics)
  • More than 30 conferences

 

Key publications

 

Experimental proof of the mechanism of Chauvin for ROMP: J.Organomet. Chem., 1978, 146, 259-265; doi:  10.1016/S0022-328X(00)88753-7.

First synthesis of natural products by RCM: Tetrahedron Lett., 1980, 21, 1715-1718; doi: 10.1016/S0040-4039(00)77818-X.

First reactions without solvent in microwaves: J. Chem. Soc. Chem. Commun., 1989, 386-387; doi: 10.1039/C39890000386.

Organometallic  under microwaves, CH activation: J. Organometal. Chem., 1994, 479, 153-157.

Chiral ionic liquid in capillary electrophoresis: J. Chrom. A, 2007, 1155, 134-141; doi: 10.1002 / ejoc.200600556.

Organic synthesis under flow: Eur. J. Org. Chem., 2010, 333-337; doi: 10.1002 / ejoc.20091032.

Enzymes supported on magnetic nanoparticles: Sensors Actuators B, 2014, 192, 269-274; doi: 10.1016 / j.snb.2013.09.096; Phosphorous, Sulfur and Silicone 2015, 190, 879-890; doi: 10.1080 / 10426507. 2014.981633.

Cheminformatics:

Neural networks in QSPR: J. Chem. Soc. Faraday Trans., 1994, 90, 97-102; doi: 10.1039 / FT9949000097.

Graph kernels and stereochemistry: Pattern Recogn. Let., 2017, 87, 227-230; doi: 10.1016 / j.patrec.2016.06.025.

 

Book

 

Phosphonic and Aminophosphonic acids. Synthesis and applications.
Mohamed Amine Didi, Didier Villemin
Editions Universitaires Européennes, OmniScriptum Publising, Saarbrücken
2018, ISBN : 978-620-2-27586-6

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